SteadyMed Ltd., an early-stage medical device company, is at the
forefront of a revolution in the personalized delivery of injectable drugs.
Whereas these drugs are normally administered in fixed doses by
medical personnel, in the future increasingly effective drug therapies
will be delivered at home under personalized control.
SteadyMed’s PatchPump is a personal “smart-package” for
delivering these liquid drugs at the rate desired, in accordance with
the patient’s individual needs. The PatchPump is a miniature patchshaped
device, adhered to the skin, which contains the drug to be
delivered and an electronic system for its delivery. A button on the
patch gives the patient control over dosing, for example, to deliver a
larger dose (a bolus) when the patient is in pain.
The injection mechanism is based on the exploitation of a side effect of
batteries – the fact that they change their volume when discharged.
SteadyMed has exploited this “bug” as an advantage – having the
expanding battery press against a flexible drug reservoir, causing the
excretion of the drug. The PatchPump can deliver drugs through
the skin either via a tiny catheter or via transdermal means such as
The device is optimized for the delivery of the new generation of
biological drugs, such as therapeutic antibodies, which specifically
target diseased cells. Many such drugs are highly viscous and/or
require sophisticated delivery regimens. SteadyMed’s PatchPump
is especially suited to “package” these drugs and deliver them in a
personalized manner to the patient.